BAG5 抗体 (AA 101-200) (AbBy Fluor® 350)
Quick Overview for BAG5 抗体 (AA 101-200) (AbBy Fluor® 350) (ABIN884438)
抗原
See all BAG5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-200
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human BAG5
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- BAG5 (BCL2-Associated Athanogene 5 (BAG5))
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别名
- BAG5
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背景
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Synonyms: BAG family molecular chaperone regulator 5, BAG 5, BAG-5, BCL2 associated athanogene 5, KIAA0873, BAG5_HUMAN.
Background: BAG5 is a member of the BAG1 related protein family. BAG1 is an anti apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL 2, Raf protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. A BAG domain near the C terminus, may bind and inhibit the chaperone activity of Hsc70/Hsp70. It has been hypothesized that the BAG5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70?s anti apoptotic function. It is believed that BAG5 will play an important role in the mechanisms of neuronal death. BAG5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/modulation of other BAG containing proteins via BAG-BAGheterodimerization.
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基因ID
- 9529
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途径
- SARS-CoV-2 Protein Interactome
抗原
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