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ASB3 抗体 (AA 21-120) (HRP)

This anti-ASB3 antibody is a 兔 多克隆 antibody detecting ASB3 in ELISA, IHC (fro) 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN883766
发货至: 中国

Quick Overview for ASB3 抗体 (AA 21-120) (HRP) (ABIN883766)

抗原

See all ASB3 抗体
ASB3 (Ankyrin Repeat and SOCS Box-Containing 3 (ASB3))

适用

  • 36
  • 22
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 34
  • 2

克隆类型

  • 34
  • 2
多克隆

标记

  • 12
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ASB3 antibody is conjugated to HRP

应用范围

  • 14
  • 13
  • 13
  • 11
  • 2
  • 2
  • 1
  • 1
ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 14
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120

    交叉反应

    人, 小鼠

    预测反应

    Rat,Dog,Cow,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human ASB3

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ASB3 (Ankyrin Repeat and SOCS Box-Containing 3 (ASB3))

    别名

    ASB3

    背景

    Synonyms: Ankyrin repeat and SOCS box containing 3, Ankyrin repeat and SOCS box containing protein 3, Ankyrin repeat and SOCS box protein 3, ASB-3, ASB3, ASB3_HUMAN, Weakly similar to ankyrin brain variant 2.

    Background: Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the elongin B and C complex. Serveral other families of proteins also contain SOCS boxes but differ from the SOCS proteins in the type of domain they contained upstream of the SOCS box. Four members of the ankyrin repeat and SOCS box-containing (ASB) protein family are identified and termed as ASB-1, ASB-2, ASB-3 and ASB-4. ASB-1 is expressed in multiple organs, including the hematopoietic compartment. ASB-1 knock-out mice display a diminution of spermatogenesis with less complete filling of seminiferous tubules. Asb-2 is a novel retinoic-acid (RA)-induced gene in acute promyelocytic leukemia (APL) cells and its expression induces growth-inhibition and chromatin condensation recapitulating early events critical to RA-induced differentiaiton of APL cells. ASB-2 is directly induced by all-trans retinotic acid, by the binding of RARa to the RAR binding element/RXR binding element in the Asb-2 promoter.

    基因ID

    51130
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