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Apelin 抗体 (AA 65-77) (AbBy Fluor® 555)

This anti-Apelin antibody (ABIN882971) is a Rabbit Polyclonal antibody detecting Apelin in IF (cc), IF (p). Suitable for Human, Rat, Mouse.
产品编号 ABIN882971
发货至: 中国

Quick Overview for Apelin 抗体 (AA 65-77) (AbBy Fluor® 555) (ABIN882971)

抗原

See all Apelin (APLN) 抗体
Apelin (APLN)

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Apelin antibody is conjugated to AbBy Fluor® 555

应用范围

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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 65-77

    特异性

    The antibody's immunogen sequence is derived from the Apelin-13 peptide. Therefore the Antibody can detect each of the active peptides that can be produced via proteolytic processing of the Apelin precursor.

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Apelin

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Apelin (APLN)

    别名

    Apelin

    背景

    Synonyms: AGTRL1 ligand, APEL, APEL_HUMAN, Apelin-13, Apelin13, Apelin 13, APJ endogenous ligand, Apln, XNPEP2

    Background: Apelin is a neuropeptide expressed in the supraoptic and paraventricular nuclei and is an endogenous ligand for APJ, a G protein-coupled orphan receptor which is an alternative coreceptor with CD4 for HIV-1. Apelin and APJ are ubiquitously expressed in peripheral tissues, with highest levels reported for heart and lungs, as well several regions within the central nervous system. The actions of apelin remain largely unknown: Apelin inhibits HIV-1 entry in cells coexpressing CD4 and APJ, the oral intake of Apelin in colostrum and breast milk could have a role in the modulation of the immune responses in neonates, more recent studies have also indicated a role for Apelin in the central control of body fluid homeostasis, by influencing AVP release and drinking behavior. In the cardiovascular system several actions of Apelin have been described, including endothelium-dependent vasodilatation, vasoconstriction through direct action on smooth muscle and positive inotropism.

    基因ID

    8862

    UniProt

    Q9ULZ1

    途径

    Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Feeding Behaviour
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