CDC14B 抗体 (AA 65-160)
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北京 101111
Quick Overview for CDC14B 抗体 (AA 65-160) (ABIN873301)
抗原
See all CDC14B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 65-160
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CDC14B
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亚型
- IgG
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anti-CDC14 Cell Division Cycle 14B (CDC14B) (AA 360-459) antibody
CDC14B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-CDC14 Cell Division Cycle 14B (CDC14B) (AA 1-471) antibodyCDC14B 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CDC14 Cell Division Cycle 14B (CDC14B) (AA 1-471) antibodyCDC14B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-CDC14 Cell Division Cycle 14B (CDC14B) (AA 188-215) antibodyCDC14B 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB16909 unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))
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别名
- CDC14B
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背景
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Synonyms: CDC14B3, Cdc14B1, Cdc14B2, hCDC14B, Dual specificity protein phosphatase CDC14B, CDC14 cell division cycle 14 homolog B, CDC14B
Background: Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases.
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基因ID
- 8555
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UniProt
- O60729
抗原
-
