COMMD7 抗体 (AA 81-170)
Quick Overview for COMMD7 抗体 (AA 81-170) (ABIN873293)
抗原
See all COMMD7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 81-170
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预测反应
- Human,Mouse,Rat,Dog,Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human COMMD7
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亚型
- IgG
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- COMMD7 (COMM Domain Containing 7 (COMMD7))
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别名
- COMMD7
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背景
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Synonyms: C20orf92, Chromosome 20 open reading frame 92, COMM domain containing 7, COMM domain containing protein 7, COMMD 7, dJ1085F17.3, FLJ14987, MGC33315, OTTHUMP00000030609, COMD7_HUMAN.
Background: COMMD is a new family of proteins with homology to MURR1, a multifunctional protein that inhibits NFkB. These proteins form multimeric complexes and were identified in a biochemical screen for MURR1-associated factors. The family is defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions. The prototype of this family, MURR1/COMMD1, suppresses NFkB by affecting the association of NF-kappaB with chromatin. COMMD7 (COMM domain-containing protein 7) interacts with COMMD1 via its COMM domain. It also associates with the NF-kappa-B complex and suppresses its transcriptional activity.
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基因ID
- 149951
抗原
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