HNE 抗体
(10 references)Quick Overview for HNE 抗体 (ABIN873270)
抗原
See all HNE 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 猴, 小鼠, 大鼠
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交叉反应 （详细）
- 4-Hydroxynonenal
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纯化方法
- Purified by Protein A.
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免疫原
- 4 Hydroxynonenal conjugated to BSA
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亚型
- IgG
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anti-4-Hydroxynonenal (HNE) antibody
HNE WB, ELISA, IHC 宿主: 小鼠 Monoclonal HNEJ-2 unconjugated
anti-4-Hydroxynonenal (HNE) antibodyHNE WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 12F7 unconjugated
anti-4-Hydroxynonenal (HNE) antibody (HRP)HNE WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 12F7 HRP
anti-4-Hydroxynonenal (HNE) antibody (FITC)HNE WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 12F7 FITC
anti-4-Hydroxynonenal (HNE) antibody (Biotin)HNE WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 12F7 Biotin
anti-4-Hydroxynonenal (HNE) antibody (PE)HNE WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 12F7 PE
anti-4-Hydroxynonenal (HNE) antibody (PerCP)HNE WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 12F7 PerCP
anti-4-Hydroxynonenal (HNE) antibody (APC)HNE WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 12F7 APC
anti-4-Hydroxynonenal (HNE) antibody (Atto 594)HNE WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 12F7 Atto 594
anti-4-Hydroxynonenal (HNE) antibody (Atto 488)HNE WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 12F7 Atto 488
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应用备注
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IHC-P 1:100-500
IF(IHC-P) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Oxidized LDL regulates efferocytosis through the CD36-PKM2-mtROS pathway." in: bioRxiv : the preprint server for biology, (2024) (PubMed).
: "Diabetes Upregulates Oxidative Stress and Downregulates Cardiac Protection to Exacerbate Myocardial Ischemia/Reperfusion Injury in Rats." in: Antioxidants (Basel, Switzerland), Vol. 9, Issue 8, (2020) (PubMed).
: "Resveratrol Restores Neuronal Tight Junction Proteins Through Correction of Ammonia and Inflammation in CCl4-Induced Cirrhotic Mice." in: Molecular neurobiology, Vol. 56, Issue 7, pp. 4718-4729, (2019) (PubMed).
: "Eupatilin exerts neuroprotective effects in mice with transient focal cerebral ischemia by reducing microglial activation." in: PLoS ONE, Vol. 12, Issue 2, pp. e0171479, (2017) (PubMed).
: "Involvement of oxidative stress in increased peripheral nerve firing during spontaneous dysesthesia in a mouse model of ischemia-reperfusion." in: Neuroscience letters, Vol. 631, pp. 109-14, (2016) (PubMed).
: "Hydrogen-rich water protects against acetaminophen-induced hepatotoxicity in mice." in: World journal of gastroenterology : WJG, Vol. 21, Issue 14, pp. 4195-209, (2015) (PubMed).
: "A novel nonhuman primate model of cigarette smoke-induced airway disease." in: The American journal of pathology, Vol. 185, Issue 3, pp. 741-55, (2015) (PubMed).
: "Pre-treatment with the synthetic antioxidant T-butyl bisphenol protects cerebral tissues from experimental ischemia reperfusion injury." in: Journal of neurochemistry, Vol. 130, Issue 6, pp. 733-47, (2014) (PubMed).
: "Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature. ..." in: The Journal of clinical investigation, Vol. 124, Issue 8, pp. 3617-33, (2014) (PubMed).
: "Neuroprotective effect of calycosin on cerebral ischemia and reperfusion injury in rats." in: Journal of ethnopharmacology, Vol. 144, Issue 3, pp. 768-74, (2012) (PubMed).
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: "Oxidized LDL regulates efferocytosis through the CD36-PKM2-mtROS pathway." in: bioRxiv : the preprint server for biology, (2024) (PubMed).
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- HNE (4-Hydroxynonenal (HNE))
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别名
- 4 Hydroxynonenal
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物质类
- Chemical
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背景
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Synonyms: 4-Hydroxy-2-Nonenal, 4Hydroxynonenal, 4-Hydroxynonenal, 4 HNE, 4HNE, 4-HNE, E-4-Hydroxynonenal-dimethylacetal, 4-HNE-DMA.
Background: Aldehydic products of lipid peroxidation, such as 4 hydroxynonenal (4 HNE), have been implicated in the etiology of pathological changes under oxidative stress as a key mediator of oxidative stress induced cell death. It is a stable product of lipid peroxidation, is proarrhythmic and may contribute to the cytotoxic effects of oxidative stress 4-HNE has been hypothesized to play a key role in cell signal transduction, in a variety of pathways from cell cycle events to cellular adhesion.
抗原
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