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FGA 抗体 (AA 61-160)

Cited in 2+ publications. This 兔 多克隆 anti-FGA antibody specifically detects FGA in WB, ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). The antibody is reactive with 大鼠 和 小鼠 samples.
产品编号 ABIN873232
发货至: 中国
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Quick Overview for FGA 抗体 (AA 61-160) (ABIN873232)

抗原

See all FGA 抗体
FGA (Fibrinogen alpha Chain (FGA))

适用

  • 65
  • 47
  • 35
  • 3
  • 2
  • 2
  • 2
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  • 1
  • 1
大鼠, 小鼠

宿主

  • 77
  • 18
  • 6
  • 2

克隆类型

  • 72
  • 31
多克隆

标记

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This FGA antibody is un-conjugated

应用范围

  • 83
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 61-160

    交叉反应

    小鼠, 大鼠

    预测反应

    Human,Dog,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Fibrinogen alpha chain

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Imamura, Yamada, Tsuboi, Nakane, Tsukasaki, Komatsuzaki, Jin: "Near-Infrared Emitting PbS Quantum Dots for in Vivo Fluorescence Imaging of the Thrombotic State in Septic Mouse Brain." in: Molecules (Basel, Switzerland), Vol. 21, Issue 8, (2016) (PubMed).

    Li, He, Di, Yan, Zhang: "Comparative analysis of the serum proteome for biomarker discovery to reveal hepatotoxicity induced by iron ion radiation in mice." in: Life sciences, Vol. 167, pp. 57-66, (2016) (PubMed).

  • 抗原

    FGA (Fibrinogen alpha Chain (FGA))

    别名

    Fibrinogen alpha chain

    背景

    Synonyms: Fib2, Fibrinogen alpha chain, FGA, Fibrin

    Background: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.

    基因ID

    2243

    UniProt

    P02671
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