TACC1 抗体 (AA 588-680)
Quick Overview for TACC1 抗体 (AA 588-680) (ABIN873222)
抗原
See all TACC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 588-680
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Cow,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human TACC1
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亚型
- IgG
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anti-Transforming, Acidic Coiled-Coil Containing Protein 1 (TACC1) (N-Term) antibody
TACC1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming, Acidic Coiled-Coil Containing Protein 1 (TACC1) (AA 11-60) antibodyTACC1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- TACC1 (Transforming, Acidic Coiled-Coil Containing Protein 1 (TACC1))
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别名
- TACC1
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背景
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Synonyms: Ga 55, Ga55, Gastric cancer antigen Ga 55, Gastric cancer antigen Ga55, KIAA1103, TACC 1, Taxin 1, Taxin1, transforming acidic coiled coil containing protein 1, DKFZp686K18126, TACC1_HUMAN.
Background: TACC1 is one of three TACC family members, which are thought to be involved in breast tumorigenesis. TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15 % of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 8, 10, and 4. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner
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基因ID
- 6867
抗原
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