PLA2G4A 抗体 (AA 501-600)
Quick Overview for PLA2G4A 抗体 (AA 501-600) (ABIN873195)
抗原
See all PLA2G4A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 501-600
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预测反应
- Human,Mouse,Rat,Dog,Pig,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CPLA2
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亚型
- IgG
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))
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别名
- CPLA2
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背景
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Synonyms: Calcium dependent phospholipid binding protein, CPLA 2, cPLA2 alpha, cPLA2, Cytosolic phospholipase A2, Cytosolic phospholipase A2 group IVA, Lysophospholipase, MGC126350, PA24A_HUMAN, Phosphatidylcholine 2 acylhydrolase, Phosphatidylcholine 2-acylhydrolase, Phospholipase A2 group 4 A, Phospholipase A2 group IVA cytosolic calcium dependent, Phospholipase A2 group IVA, PhospholipaseA2, PLA2G4.
Background: This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. [provided by RefSeq, Jul 2008].
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基因ID
- 5321
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途径
- Inositol Metabolic Process, G-protein mediated Events, VEGF Signaling
抗原
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