SHoc2/Sur8 抗体 (AA 36-120)
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北京 101111
Quick Overview for SHoc2/Sur8 抗体 (AA 36-120) (ABIN873061)
抗原
See all SHoc2/Sur8 (SHOC2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 36-120
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Sheep,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SHOC2/Sur8
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亚型
- IgG
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anti-Leucine-rich repeat protein SHOC-2 (SHOC2) (AA 3-89) antibody
SHOC2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-rich repeat protein SHOC-2 (SHOC2) (C-Term) antibodySHOC2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leucine-rich repeat protein SHOC-2 (SHOC2) (AA 1-280) antibodySHOC2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-rich repeat protein SHOC-2 (SHOC2) (AA 56-83), (N-Term) antibodySHOC2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB37466 unconjugated
anti-Leucine-rich repeat protein SHOC-2 (SHOC2) (N-Term) antibodySHOC2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- SHoc2/Sur8 (SHOC2) (Leucine-rich repeat protein SHOC-2 (SHOC2))
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别名
- SHOC2
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背景
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Synonyms: Leucine-rich repeat protein SHOC-2, Leucine-rich repeat protein SHOC-2, Ras-binding protein Sur-8, KIAA0862, Leucine-rich repeat protein SHOC-2, Protein soc-2 homolog, Protein Sur-8 homolog, SHOC2, SHOC2_HUMAN.
Background: Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.Involvement in disease:Defects in SHOC2 are the cause of Noonan syndrome-like with loose anagen hair (NSLAH) . NSLAH children display macrocephaly, high forehead, hypertelorism, palpebral ptosis, low-set and posteriorly rotated ears, short and webbed neck and pectus anomalies. Affected subjects also have easily pluckable, sparse, thin and slow-growing hair.
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基因ID
- 8036
抗原
-
