CLPTM1L 抗体 (AA 165-270)
Quick Overview for CLPTM1L 抗体 (AA 165-270) (ABIN873033)
抗原
See all CLPTM1L 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 165-270
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预测反应
- Human,Mouse,Rat,Dog,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CLPTM1L/CRR9
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亚型
- IgG
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- CLPTM1L (CLPTM1-Like (CLPTM1L))
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别名
- CRR9
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背景
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Synonyms: Cisplatin resistance related protein 9, Cisplatin resistance related protein CRR9p, Cisplatin resistance-related protein 9, Cleft lip and palate transmembrane protein 1 like protein, Cleft lip and palate transmembrane protein 1-like protein, CLP1L_HUMAN, CLPTM1 like, CLPTM1 like protein, CLPTM1-like protein, CLPTM1L, CRR9, CRR9p.
Background: Clefts of the oral-facial region usually occur in early fetal development and can affect the lip, the soft palate and the hard palate. Cleft lip (with or without cleft palate) is a genetically complex birth defect that occurs in approximately one in every 750-1,000 live births. This is one of the most common birth defects and is multifactorial, with both genetic and environmental causes. Cleft lip- and palate-associated transmembrane protein 1 (CLPTM1) belongs to a family of cleft lip and palate transmembrane proteins. This family also contains cisplatin resistance-related protein (CRR9), which is involved in CDDP-induced apoptosis. CLPTM1L (cleft lip and palate transmembrane protein 1-like protein), also known as CRR9p (cisplatin resistance-related protein 9) is a 538 amino acid multi-pass membrane protein that belongs to the CLPTM1 family and, when overexpressed, enhances cisplatin-mediated apoptosis. CLPTM1L exists as two alternatively spliced isoforms encoded by a gene that maps to human chromosome 5p15.33.
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基因ID
- 81037
抗原
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