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APOB 抗体 (AA 1501-1700)

This anti-APOB antibody is a 兔 多克隆 antibody detecting APOB in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN872950
发货至: 中国

Quick Overview for APOB 抗体 (AA 1501-1700) (ABIN872950)

抗原

See all APOB 抗体
APOB (Apolipoprotein B (APOB))

适用

  • 127
  • 35
  • 34
  • 10
  • 3

宿主

  • 90
  • 68
  • 14
  • 2
  • 2

克隆类型

  • 97
  • 77
多克隆

标记

  • 92
  • 27
  • 21
  • 7
  • 6
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This APOB antibody is un-conjugated

应用范围

  • 112
  • 81
  • 64
  • 45
  • 44
  • 18
  • 17
  • 14
  • 7
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 8
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1501-1700

    预测反应

    Human,Mouse,Rat,Dog,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Apolipoprotein B

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Choi, de Poot, Lee, Kim, Han, Kim, Finley, Lee: "Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation." in: Nature communications, Vol. 7, pp. 10963, (2016) (PubMed).

  • 抗原

    APOB (Apolipoprotein B (APOB))

    别名

    Apolipoprotein B

    背景

    Synonyms: Apo B 100, Apo B, Apo B-100, Apo B-48, ApoB 100, ApoB 48, ApoB, APOB protein, APOB_HUMAN, Apolipoprotein B 100, Apolipoprotein B 48, Apolipoprotein B, Apolipoprotein B-48, FLDB.

    Background: Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.Involvement in disease: Defects in APOB are a cause of hypobetalipoproteinemia familial type 1 (FHBL1) . A disorder characterized by highly reduced plasma concentrations of low density lipoproteins, and dietary fat malabsorption. Clinical presentation may vary from no symptoms to severe gastrointestinal and neurological dysfunction similar to abetalipoproteinemia.Defects in APOB are a cause of familial ligand-defective apolipoprotein B-100 (FDB). FDB is a dominantly inherited disorder of lipoprotein metabolism leading to hypercholesterolemia and increased proneness to coronary artery disease (CAD). The plasma cholesterol levels are dramatically elevated due to impaired clearance of LDL particles by defective APOB/E receptors.

    基因ID

    338

    途径

    Lipid Metabolism
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