FAM134C 抗体 (AA 76-180)
Quick Overview for FAM134C 抗体 (AA 76-180) (ABIN872917)
抗原
See all FAM134C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 76-180
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human FAM134C
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亚型
- IgG
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anti-Family with Sequence Similarity 134, Member C (FAM134C) (AA 36-85) antibody
FAM134C 适用: 小鼠, 人, 大鼠, Cow, 犬, 马, 兔, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- FAM134C (Family with Sequence Similarity 134, Member C (FAM134C))
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别名
- Fam134c
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背景
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Synonyms: Protein FAM134C, FAM134C
Background: Chromosome 17 makes up over 2.5 % of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17. The FAM134C gene product has been provisionally designated FAM134C pending further characterization.
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基因ID
- 162427
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UniProt
- Q86VR2
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途径
- SARS-CoV-2 Protein Interactome
抗原
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