TNIP2 抗体 (AA 85-180)
Quick Overview for TNIP2 抗体 (AA 85-180) (ABIN872901)
抗原
See all TNIP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 85-180
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交叉反应
- 人, 大鼠
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预测反应
- Mouse,Dog,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human TNIP2/ABIN2
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亚型
- IgG
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anti-TNFAIP3 Interacting Protein 2 (TNIP2) (Center) antibody
TNIP2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 2 (TNIP2) (AA 61-110) antibodyTNIP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 2 (TNIP2) (AA 170-413) antibodyTNIP2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 2 (TNIP2) antibodyTNIP2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 2 (TNIP2) (AA 240-429) antibodyTNIP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 2 (TNIP2) (AA 20-200) antibodyTNIP2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- TNIP2 (TNFAIP3 Interacting Protein 2 (TNIP2))
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别名
- TNIP2
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背景
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Synonyms: KLIP, ABIN2, FLIP1, TNFAIP3-interacting protein 2, A20-binding inhibitor of NF-kappa-B activation 2, ABIN-2, Fetal liver LKB1-interacting protein, TNIP2
Background: Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation. Involved in activation of the MEK/ERK signaling pathway during innate immune response, this function seems to be stimulus- and cell type specific. Required for stability of MAP3K8. Involved in regulation of apoptosis in endothelial cells, promotes TEK agonist-stimulated endothelial survival. May act as transcriptional coactivator when translocated to the nucleus. Enhances CHUK-mediated NF-kappa-B activation involving NF-kappa-B p50-p65 and p50-c-Rel complexes.
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基因ID
- 79155
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UniProt
- Q8NFZ5
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途径
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin
抗原
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