ARRDC3 抗体 (AA 178-215)
Quick Overview for ARRDC3 抗体 (AA 178-215) (ABIN872868)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 178-215
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ARRDC3 corresponding to amino acids 178-215.
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亚型
- IgG
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anti-Arrestin Domain Containing 3 (ARRDC3) (C-Term) antibody
ARRDC3 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Arrestin Domain Containing 3 (ARRDC3) (C-Term) antibodyARRDC3 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, IP, IC 宿主: 兔 Polyclonal unconjugated
anti-Arrestin Domain Containing 3 (ARRDC3) (AA 1-270) antibodyARRDC3 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Arrestin Domain Containing 3 (ARRDC3) (AA 365-414) antibodyARRDC3 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- ARRDC3 (Arrestin Domain Containing 3 (ARRDC3))
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别名
- ARRDC3
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背景
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Synonyms: ARRDC 3, Arrestin domain containing protein 3, KIAA1376, Thioredoxin binding protein 2 like inducible membrane, TLIMP, ARRD3_HUMAN.
Background: The arrestins are a family of proteins that are important for regulating signal transduction within cells. Arrestins are part of a conserved two step mechanism for regulating the activity of G-protein coupled receptors (GPCRs). In response to a stimulus, GPCRs activate a heterotrimeric G protein. In order to turn off this response, or adapt to a constant stimulus, activated receptors need to be silenced. The first step is phosphorylation by a class of serine/threonine kinases called G protein coupled receptor kinases (GRKs). This phosphorylation specifically marks the activated receptor for arrestin binding. Once arrestin is bound to the receptor it is unable to signal further. Recent research continues to expand the known actions of arrestins, which can bind to other classes of receptors and can directly activate signaling pathways on their own. Different arrestins (visual arrestin (or Arrestin 1), beta-arrestin 1 (or Arrestin 2) and beta-arrestin 2 (or Arrestin 3) can reduce the activity of their target GPCRs in several different ways.
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基因ID
- 57561
抗原
-
