BRCC3 抗体 (AA 21-120)
Quick Overview for BRCC3 抗体 (AA 21-120) (ABIN872718)
抗原
See all BRCC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-120
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human BRCC3/BRCC36
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亚型
- IgG
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anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 14-316) antibody
BRCC3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 1-316) antibodyBRCC3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 1-316), (N-Term) antibodyBRCC3 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal AT3B1 unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 1-316) antibodyBRCC3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 36-70) antibodyBRCC3 适用: 人 WB 宿主: 兔 Polyclonal RB54401 unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 18-50) antibodyBRCC3 适用: 人 WB 宿主: 兔 Polyclonal RB53911 unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) antibody (FITC)BRCC3 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal FITC
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (C-Term) antibodyBRCC3 适用: 人, 小鼠, 大鼠, 马, Pig, 猴, Cow, 豚鼠, 兔, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (C-Term) antibodyBRCC3 适用: 人, 大鼠, 马, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 1-316) antibodyBRCC3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal AT3B1 unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- BRCC3 (BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3))
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别名
- BRCC36
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背景
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Synonyms: BRCA1-A complex subunit BRCC36, BRCA1/BRCA2 containing complex subunit 3, BRCA1/BRCA2 containing complex subunit 36, BRCA1/BRCA2-containing complex subunit 3, BRCA1/BRCA2-containing complex subunit 36, Brcc3, BRCC3_HUMAN, BRCC36, BRISC complex subunit BRCC36, C6.1A, Chromosome X open reading frame 53, CXorf53, Lys-63-specic deubiquitinase BRCC36.
Background: Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not have activity toward 'Lys-48'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). In the BRCA1-A complex, it specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX, antagonizing the RNF8-dependent ubiquitination at double-strand breaks (DSBs). Catalytic subunit of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex.
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基因ID
- 79184
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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