FAIM2 抗体 (AA 211-316)
Quick Overview for FAIM2 抗体 (AA 211-316) (ABIN872627)
抗原
See all FAIM2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 211-316
-
预测反应
- Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Chicken,Rabbit,Monkey
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human FAIM2
-
亚型
- IgG
-
-
anti-Fas Apoptotic Inhibitory Molecule 2 (FAIM2) (AA 1-316) antibody
FAIM2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule 2 (FAIM2) (AA 1-316) antibodyFAIM2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C2 unconjugated
anti-Fas Apoptotic Inhibitory Molecule 2 (FAIM2) (AA 1-105) antibodyFAIM2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule 2 (FAIM2) (N-Term) antibodyFAIM2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- FAIM2 (Fas Apoptotic Inhibitory Molecule 2 (FAIM2))
-
别名
- FAIM2
-
背景
-
Synonyms: FAIM 2, Fas apoptotic inhibitory molecule 2, LFG, Leguard, Neural membrane protein 35, NGP 35, NGP35, NMP 35, NMP35, Protein leguard, TMBIM 2, TMBIM2, Transmembrane BAX inhibitor mot containing 2, Transmembrane BAX inhibitor mot containing protein 2, LFG2_HUMAN.
Background: Programmed cell death regulates a number of biological processes such as normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. FAIM2 is a recently identified protein that can inhibit the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-alpha death signal. In this respect, FAIM2 is functionally similar to the anti-apoptotic proteins FAIM, FLIP and Bcl-xL. FAIM2, a seven membrane spanning protein, can bind the Fas receptor but does not regulate Fas expression or inhibit binding of FADD to Fas. FAIM2 is widely distributed, but highly expressed in the hippocampus and other neural tissues. FAIM2 was also identified as the neural membrane protein 35 (NMP35) and its expression is known to be regulated by the Phosphatidylinositol 3-kinase-Akt/PKB pathway.
-
基因ID
- 23017
抗原
-
