MORF4L1 抗体 (AA 261-360)
Quick Overview for MORF4L1 抗体 (AA 261-360) (ABIN872616)
抗原
See all MORF4L1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 261-360
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预测反应
- Human,Mouse,Rat,Dog,Cow,Zebrafish
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Mortality factor 4-like protein 1/SEN1
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))
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别名
- Mortality factor 4-like protein 1
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背景
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Synonyms: Cell senescence related gene complementation group B, Cellular senescence related protein 1, CSR, CSRB, MORF 4, MORF4, MORF4 protein, Mortality factor 4, SEN 1, SEN, Senescence cellular related 1, Senescence related cellular 1, Transcription factor like protein MORF4, MO4L1_HUMAN, Mortality factor 4-like protein 1, MORF-related gene 15 protein, Protein MSL3-1, Transcription factor-like protein MRG15.
Background: Cellular senescence, the terminal nondividing state that normal cells enter following completion of their proliferative potential, is the dominant phenotype in hybrids of normal and immortal cells. Fusions of immortal human cell lines with each other have led to their assignment to one of several complementation groups. SEN1 or MORF4 is a gene on chromosome 4 that induces a senescent-like phenotype in cell lines assigned to complementation group B. It is capable of reversing the immortal phenotype of a subset of immortal cells. Overexpression of SEN1 in HeLa cells ultimately caused abnormal nuclear morphology and cell death.
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基因ID
- 10934
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途径
- Chromatin Binding
抗原
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