MORF4L1 抗体 (AA 261-360)
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- 抗原 See all MORF4L1 抗体
- MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))
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抗原表位
- AA 261-360
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MORF4L1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Zebrafish
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Mortality factor 4-like protein 1/SEN1
- 亚型
- IgG
- Top Product
- Discover our top product MORF4L1 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))
- 别名
- Mortality factor 4-like protein 1 (MORF4L1 产品)
- 背景
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Synonyms: Cell senescence related gene complementation group B, Cellular senescence related protein 1, CSR, CSRB, MORF 4, MORF4, MORF4 protein, Mortality factor 4, SEN 1, SEN, Senescence cellular related 1, Senescence related cellular 1, Transcription factor like protein MORF4, MO4L1_HUMAN, Mortality factor 4-like protein 1, MORF-related gene 15 protein, Protein MSL3-1, Transcription factor-like protein MRG15.
Background: Cellular senescence, the terminal nondividing state that normal cells enter following completion of their proliferative potential, is the dominant phenotype in hybrids of normal and immortal cells. Fusions of immortal human cell lines with each other have led to their assignment to one of several complementation groups. SEN1 or MORF4 is a gene on chromosome 4 that induces a senescent-like phenotype in cell lines assigned to complementation group B. It is capable of reversing the immortal phenotype of a subset of immortal cells. Overexpression of SEN1 in HeLa cells ultimately caused abnormal nuclear morphology and cell death.
- 基因ID
- 10934
- 途径
- Chromatin Binding
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