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NSD1 抗体 (AA 2401-2600)

This anti-NSD1 antibody is a 兔 多克隆 antibody detecting NSD1 in ELISA, IF (cc), IF (p), IHC (fro) 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN872593
发货至: 中国

Quick Overview for NSD1 抗体 (AA 2401-2600) (ABIN872593)

抗原

See all NSD1 抗体
NSD1 (Nuclear Receptor Binding SET Domain Protein 1 (NSD1))

适用

  • 30
  • 16
  • 14
  • 1
人, 小鼠, 大鼠

宿主

  • 22
  • 10

克隆类型

  • 23
  • 9
多克隆

标记

  • 12
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NSD1 antibody is un-conjugated

应用范围

  • 12
  • 12
  • 10
  • 7
  • 2
  • 2
  • 2
  • 1
  • 1
ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 14
    • 3
    • 2
    AA 2401-2600

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Sheep,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human NSD1

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    NSD1 (Nuclear Receptor Binding SET Domain Protein 1 (NSD1))

    别名

    Nsd1

    背景

    Synonyms: Androgen receptor coactivator 267 kDa protein, Androgen receptor-associated protein of 267 kDa, ARA267, H3 K36 HMTase, H3-K36-HMTase, H4 K20 HMTase, H4-K20-HMTase, Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specic, KMT3B, Lysine N-methyltransferase 3B, NR binding SET domain containing protein, NR-binding SET domain-containing protein, Nsd1, NSD1_HUMAN, Nuclear receptor binding SET domain containing protein 1, Nuclear receptor-binding SET domain-containing protein 1.

    Background: This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].

    基因ID

    64324
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