COMMD10 抗体 (AA 91-190)
Quick Overview for COMMD10 抗体 (AA 91-190) (ABIN872531)
抗原
See all COMMD10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 91-190
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human COMMD10
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亚型
- IgG
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anti-COMM Domain Containing 10 (COMMD10) (AA 1-202) antibody
COMMD10 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- COMMD10 (COMM Domain Containing 10 (COMMD10))
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别名
- Commd10
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背景
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Synonyms: COMM domain containing 10, COMMD 10, FLJ11285, HGNC:30201, HSPC305, PTD002.
Background: COMMD or COMM is a new family of proteins with homology to MURR1, a multifunctional protein that inhibits NFkB. These proteins form multimeric complexes and were identified in a biochemical screen for MURR1-associated factors. The family is defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions. The proteins designated as COMMD or COMM domain containing 1-10 are extensively conserved in multicellular eukaryotic organisms and define a novel family of structural and functional homologs of MURR1. The prototype of this family, MURR1/COMMD1, suppresses NFkB not by affecting nuclear translocation or binding of NF-kappaB to cognate motifs, rather, it functions in the nucleus by affecting the association of NF-kappaB with chromatin.
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基因ID
- 51397
抗原
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