COMMD1 抗体 (AA 95-190)
Quick Overview for COMMD1 抗体 (AA 95-190) (ABIN872509)
抗原
See all COMMD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 95-190
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Cow,Sheep,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human COMMD1/MURR1
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- COMMD1 (Copper Metabolism (Murr1) Domain Containing 1 (COMMD1))
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别名
- COMMD1
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背景
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Synonyms: C2orf5, COMD1, COMD1_HUMAN, COMM domain-containing protein 1, COMMD1, copper metabolism domain containing 1, MGC27155, MURR1, Protein Murr1.
Background: Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF-kappa-B activity. Down-regulates SOD1 activity by interfering with its homodimerization. Plays a role in copper ion homeostasis. Can bind one copper ion per monomer. May function to facilitate biliary copper excretion within hepatocytes.Tissue specificity:Ubiquitous. Highest expression in the liver, with lower expression in brain, lung, placenta, pancreas, small intestine, heart, skeletal muscle, kidney and placenta.
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基因ID
- 150684
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途径
- Transition Metal Ion Homeostasis
抗原
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