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Corin 抗体 (AA 165-245)

This anti-Corin antibody is a 兔 多克隆 antibody detecting Corin in ELISA 和 IF (cc). Suitable for 人, 大鼠 和 绵羊. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN872360
发货至: 中国

Quick Overview for Corin 抗体 (AA 165-245) (ABIN872360)

抗原

See all Corin (CORIN) 抗体
Corin (CORIN) (Corin, Serine Peptidase (CORIN))

适用

  • 47
  • 27
  • 20
  • 14
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
人, 大鼠, 绵羊

宿主

  • 53
  • 7
  • 1

克隆类型

  • 54
  • 7
多克隆

标记

  • 37
  • 6
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Corin antibody is un-conjugated

应用范围

  • 44
  • 27
  • 21
  • 21
  • 14
  • 12
  • 3
  • 1
  • 1
ELISA, Immunofluorescence (Cultured Cells) (IF (cc))
  • 抗原表位

    • 14
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 165-245

    交叉反应

    人, 大鼠, 绵羊

    预测反应

    Mouse,Dog,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Corin

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Miyazaki, Nishizawa, Kambayashi, Ito, Noda, Terasawa, Kato, Miyamura, Shiogama, Sekiya, Kurahashi, Fujii: "Increased levels of soluble corin in pre-eclampsia and fetal growth restriction." in: Placenta, Vol. 48, pp. 20-25, (2017) (PubMed).

    Sari, Rufaut, Jones, Sinclair: "Characterization of Ovine Dermal Papilla Cell Aggregation." in: International journal of trichology, Vol. 8, Issue 3, pp. 121-9, (2016) (PubMed).

  • 抗原

    Corin (CORIN) (Corin, Serine Peptidase (CORIN))

    别名

    Corin

    背景

    Synonyms: CRN, ATC2, Lrp4, PEE5, TMPRSS10, Atrial natriuretic peptide-converting enzyme, Corin, Heart-specific serine proteinase ATC2, Pro-ANP-converting enzyme, Transmembrane protease serine 10

    Background: Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. Isoform 2: has weaker endopeptidase activity compared to isoform 1.

    基因ID

    10699

    UniProt

    Q9Y5Q5

    途径

    Regulation of Systemic Arterial Blood Pressure by Hormones
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