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CD22 抗体 (AA 839-843)

The 兔 多克隆 anti-CD22 antibody is suitable to detect CD22 in samples from 人. It has been validated for WB.
产品编号 ABIN871688
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD22 抗体 (AA 839-843) (ABIN871688)

抗原

See all CD22 抗体
CD22 (CD22 Molecule (CD22))

适用

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宿主

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克隆类型

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多克隆

标记

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This CD22 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 839-843

    特异性

    The antibody detects endogenous level of total CD22 protein.

    纯化方法

    Affinity purified

    免疫原

    Peptide sequence around AA 839-843 (N-V-D-Y-V) derived from Human CD22. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
  • 应用备注

    Western blotting: 1:500-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    CD22 (CD22 Molecule (CD22))

    别名

    CD22

    背景

    Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins, one of which is CD45. Preferentially binds to a-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

    分子量

    140 kDa

    基因ID

    933

    NCBI登录号

    NP_001762

    UniProt

    P20273
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