RUNX1 抗体 (AA 6-10)
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北京 101111
Quick Overview for RUNX1 抗体 (AA 6-10) (ABIN871507)
抗原
See all RUNX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 6-10
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特异性
- The antibody detects endogenous level of total AML1 (RUNX1) protein.
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纯化方法
- Affinity purified
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免疫原
- Peptide sequence around AA 6-10 (D-A-S-T-S) derived from Human AML1 (RUNX1) . Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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应用备注
- Western blotting: 1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
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别名
- AML1 (RUNX1)
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背景
- CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The a subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits MYST4-dependent transcriptional activation.
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分子量
- 55 kDa
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基因ID
- 861
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NCBI登录号
- NP_001116
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UniProt
- Q01196
抗原
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