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HSPG 抗体

This anti-HSPG antibody is a 小鼠 单克隆 antibody detecting HSPG in IHC, WB 和 ELISA. Suitable for 人.
产品编号 ABIN870827
发货至: 中国

Quick Overview for HSPG 抗体 (ABIN870827)

抗原

See all HSPG 抗体
HSPG (Heparan Sulphate Protoglycans (HSPG))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This HSPG antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB), ELISA

克隆位点

2E2-B5
  • 特异性

    Monoclonal Ab 2E2/B5 is specific for a core protein epitope of a human small basement membrane heparan sulfate proteoglycan (HS-PG). mAb 2E2/B5 recognizes an epitope different from that recognized by mAb 1F10/B8 and mAb 2H7/G11. Whereas previously perlecan was the only known basement membrane HS-PG, there is now evidence that at least two other basement membrane HS-PG exist: Agrin, originally discovered as an important component of the neuromuscular junction, and a novel small HS-PG which was isolated from human aorta and kidney. This HS-PG, with a molecular weight of 80-200 kDa (aorta) and 30-160 kDa (kidney) and a core protein size of 24 kDa or 22 kDa, respectively, was localized by immunohistochemistry to the basement membrane. Amino acid sequence analysis of tryptic peptides indicate, that this small HS-PG is clearly distinct from perlecan and agrin.

    纯化方法

    Purified human small basement membrane heparan sulfate proteoglycan (HS-PG). Protein G purified.

    亚型

    IgG1 kappa
  • 应用备注

    ELISA (less than 1 µg/ml), Western Blot (1 µg/ml), immunohistochemistry (1 µg/ml) This antibody has not been tested for use in all applications. This does not necessarily exclude its use for non-tested procedures. The stated dilutions are recommendations only.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Resuspend in aqua bidest.

    缓冲液

    50 mM TRIS pH 7.4

    储存条件

    4 °C
  • 抗原

    HSPG (Heparan Sulphate Protoglycans (HSPG))

    别名

    Heparan-Sulfate-Proteoglycan
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