Neuropilin 1 抗体
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北京 101111
Quick Overview for Neuropilin 1 抗体 (ABIN866080)
抗原
See all Neuropilin 1 (NRP1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody is produced by immunizing mouse with recombinant protein Neuropilin-1.
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交叉反应
- 小鼠
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产品特性
- Positive Control: Recombinant protein. Cellular Localization: Cell membrane, secretory protein
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亚型
- IgM
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应用备注
- WB 1:1,000~1:2,000. ICC 1:100~1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.17mg/ml
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缓冲液
- 1xTBS (pH7.4), 0.5% BSA, 25% Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- Neuropilin 1 (NRP1)
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别名
- Neuropilin-1
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背景
- Neuropilin-1 is a single-pass type I membrane protein, which has two isoforms. The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. The soluble isoform 2 binds VEGF-165 (vascular endothelial growth factor165) and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. Its expression has an averse effect on blood vessel number and integrity.
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分子量
- 47kDa
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UniProt
- P97333
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途径
- Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
抗原
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