NRP1
适用: 人, 大鼠
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
应用备注
WB 1:1,000~1:2,000. ICC 1:100~1:200
限制
仅限研究用
状态
Liquid
浓度
0.17mg/ml
缓冲液
1xTBS (pH7.4), 0.5% BSA, 25% Glycerol
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
抗原
Neuropilin 1 (NRP1)
别名
Neuropilin-1
背景
Neuropilin-1 is a single-pass type I membrane protein, which has two isoforms. The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. The soluble isoform 2 binds VEGF-165 (vascular endothelial growth factor165) and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. Its expression has an averse effect on blood vessel number and integrity.