Ataxin 1 抗体
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北京 101111
Quick Overview for Ataxin 1 抗体 (ABIN865485)
抗原
See all Ataxin 1 (ATXN1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human ATXN1 expressed in E. Coli.
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亚型
- IgG1
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应用备注
- WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF: 1/200 - 1/1000, FC: 1/200-1/400 ELISA: Propose dilution 1/10000. Figure 3: Immunofluorescence
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100g/100l
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- Ataxin 1 (ATXN1)
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别名
- ATXN1
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背景
- The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. Synonyms: ATX1, SCA1, D6S504E, ATXN1
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分子量
- 87kDa
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基因ID
- 6310
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途径
- Synaptic Membrane
抗原
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