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EIF4E 抗体

EIF4E 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 小鼠 Monoclonal 5D11 unconjugated
产品编号 ABIN865450
发货至: 中国
  • 抗原 See all EIF4E 抗体
    EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This EIF4E antibody is un-conjugated
    应用范围
    • 95
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human EIF4E expressed in E. Coli.
    克隆位点
    5D11
    亚型
    IgG1
    Top Product
    Discover our top product EIF4E Primary Antibody
  • 应用备注
    WB: 1/500 - 1/2000, IHC: 1/200-1/1000, IF: 1/200-1/1000, FC: 1/200-1/400, ELISA: Propose dilution 1/10000.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100g/100l
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
    别名
    EIF4E (EIF4E 产品)
    背景
    EIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. Several kinases are currently being investigated as potential regulators of eIF4E including PKC and/or the MAP kinase activated Mnk. Synonyms: CBP, EIF4F, EIF4E1, EIF4EL1, MGC111573, EIF4E
    分子量
    25kDa
    基因ID
    1977
    途径
    BCR Signaling
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