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B-Cell Linker 抗体

BLNK 适用: 人, 小鼠 WB, ELISA, IHC, FACS, IF 宿主: 小鼠 Monoclonal 5G9 unconjugated
产品编号 ABIN865398
发货至: 中国
  • 抗原 See all B-Cell Linker (BLNK) 抗体
    B-Cell Linker (BLNK)
    适用
    • 96
    • 68
    • 38
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 106
    • 8
    • 1
    小鼠
    克隆类型
    • 107
    • 8
    单克隆
    标记
    • 49
    • 7
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    • 4
    • 4
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    • 4
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    • 4
    • 4
    • 2
    • 1
    This B-Cell Linker antibody is un-conjugated
    应用范围
    • 108
    • 52
    • 36
    • 26
    • 20
    • 19
    • 18
    • 8
    • 6
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human BLNK expressed in E. Coli.
    克隆位点
    5G9
    亚型
    IgG1
    Top Product
    Discover our top product BLNK Primary Antibody
  • 应用备注
    WB: 1/500 - 1/2000, IHC: 1/200-1/1000, IF: 1/200-1/1000, FC: 1/200-1/400, ELISA: Propose dilution 1/10000.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100g/100l
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    B-Cell Linker (BLNK)
    别名
    BLNK (BLNK 产品)
    别名
    BLNK antibody, blnk antibody, MGC147045 antibody, BASH antibody, Bca antibody, Ly-57 antibody, Ly57 antibody, Lyw-57 antibody, SLP-65 antibody, AGM4 antibody, BLNK-S antibody, LY57 antibody, SLP65 antibody, bca antibody, B-cell linker antibody, B cell linker antibody, BLNK antibody, blnk antibody, Blnk antibody
    背景
    This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Synonyms: AGM4, BASH, LY57, SLP65, BLNK-S, SLP-65, MGC111051
    分子量
    68kDa
    基因ID
    29760
    途径
    BCR Signaling
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