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DUX4 抗体 (C-Term)

This anti-DUX4 antibody is a 小鼠 单克隆 antibody detecting DUX4 in WB, IHC, IF 和 ICC. Suitable for 人.
产品编号 ABIN863109
发货至: 中国

Quick Overview for DUX4 抗体 (C-Term) (ABIN863109)

抗原

See all DUX4 抗体
DUX4 (Double Homeobox 4 (DUX4))

适用

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  • 8
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  • 1
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宿主

  • 51
  • 13
小鼠

克隆类型

  • 51
  • 11
单克隆

标记

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  • 3
  • 1
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  • 1
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  • 1
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This DUX4 antibody is un-conjugated

应用范围

  • 52
  • 23
  • 15
  • 13
  • 13
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  • 10
  • 4
  • 3
  • 2
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  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

P2B1
  • 抗原表位

    • 16
    • 15
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    C-Term

    特异性

    Detects ~45 kDa. No cross-reactivity with DUX4c.

    交叉反应

    人, 小鼠

    纯化方法

    Protein G Purified

    免疫原

    C-terminal 76 amino acids of DUX4 with glutathione-s-transferase (gst) tag

    亚型

    IgG1
  • 应用备注

    • WB (1:1000)
    • ICC/IF (1:1000)
    • optimal dilutions for assays should be determined by the user.

    说明

    1 μg/ml of ABIN863109 was sufficient for detection of DUX4 in 20 μg of HeLa cell lysate by ECL immunoblot analysis using goat anti-mouse IgG: HRP as teh secondary.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C
  • 抗原

    DUX4 (Double Homeobox 4 (DUX4))

    别名

    DUX4

    背景

    DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1 (1). Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function (2-4). In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues (5).

    基因ID

    22947

    NCBI登录号

    NP_149418

    UniProt

    F5GZ66
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