MBP 抗体 (pThr232)
Quick Overview for MBP 抗体 (pThr232) (ABIN802593)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pThr232
-
特异性
- This antibody recognizes Thr229 in mice and Thr122 in rat
-
交叉反应
- 人, 小鼠, 大鼠
-
预测反应
- Dog,Cow,Pig,Horse,Chicken,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic phosphopeptide derived from human MBP around the phosphorylation site of Thr232
-
亚型
- IgG
-
-
anti-MBP (AA 69-85) antibody
适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-MBP (AA 1-197) antibody适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-MBP (AA 182-197), (C-Term) antibody适用: 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-MBP antibody适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 10C12 unconjugated
anti-MBP antibody适用: 人 WB, IF 宿主: 小鼠 Monoclonal 408CT17-4-3 unconjugated
-
-
应用备注
-
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- MBP
-
背景
-
Synonyms: Myelin basic protein, MBP, Myelin A1 protein, Myelin membrane encephalitogenic protein
Background: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
-
基因ID
- 4155
-
UniProt
- P02686
抗原
-
