IFNAR1 抗体 (pSer535, pSer538)
Quick Overview for IFNAR1 抗体 (pSer535, pSer538) (ABIN802353)
抗原
See all IFNAR1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer535, pSer538
-
交叉反应
- 人, 大鼠
-
预测反应
- Mouse,Dog,Cow,Sheep,Pig,Horse,Guinea Pig
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic phosphopeptide derived from human IFNAR1 around the phosphorylation site of Ser535+Ser538
-
亚型
- IgG
-
-
-
-
应用备注
-
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
-
别名
- IFNAR1 +
-
背景
-
Synonyms: AVP, IFRC, IFNAR, IFNBR, IFN-alpha-REC, Interferon alpha/beta receptor 1, IFN-R-1, IFN-alpha/beta receptor 1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, CRF2-1, Type I interferon receptor 1, IFNAR1
Background: Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. Can also transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.
-
基因ID
- 3454
-
UniProt
- P17181
-
途径
- JAK/STAT Signaling, Hepatitis C
抗原
-