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GRIN2B 抗体 (pTyr1252)

Name: GRIN2B 抗体 (pTyr1252)
SKU: ABIN801213
Availability: OutOfStock

This anti-GRIN2B antibody is a 兔多克隆 antibody detecting GRIN2B in WB 和 ELISA. Suitable for 大鼠.

Formalin-fixed and paraffin embedded rat brain (epencephala) labeled with Rabbit Anti Phospho-NMDAR2B (Tyr1252) Polyclonal Antibody, Unconjugated (ABIN801213) at 1:200 followed by conjugation to the secondary antibody and DAB staining (GRIN2B 抗体 (pTyr1252))

IHC

Formalin-fixed and paraffin-embedded rat brain labeled with Anti-Phospho-NMDAR2B (Tyr1252) Polyclonal Antibody, Unconjugated (ABIN801213) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C. (GRIN2B 抗体 (pTyr1252))

2 images

产品编号 ABIN801213

发货至: 中国

Quick Overview for GRIN2B 抗体 (pTyr1252) (ABIN801213)

抗原

See all GRIN2B 抗体

GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

适用

大鼠

宿主

兔

克隆类型

多克隆

标记

This GRIN2B antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA

Discover our top product GRIN2B Primary Antibody

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pTyr1252

特异性

This antibody may cross react with NMDAR2A (Tyr 1246) due to 75 % sequence similarity.

预测反应

Human,Mouse,Dog,Cow,Chicken,Rabbit,Guinea Pig

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic phosphopeptide derived from human NMDAR2B around the phosphorylation site of Tyr1252

亚型

IgG
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 27-163) antibody
GRIN2B 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6E9A8 unconjugated

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (HRP)
GRIN2B 适用: 大鼠 WB, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal S59 HRP

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (FITC)
GRIN2B 适用: 大鼠 WB, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal S59 FITC

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (Biotin)
GRIN2B 适用: 大鼠 WB, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal S59 Biotin

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (PE)
GRIN2B 适用: 大鼠 WB, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal S59 PE

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (APC)
GRIN2B 适用: 大鼠 WB, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal S59 APC

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (PerCP)
GRIN2B 适用: 大鼠 WB, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal S59 PerCP

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (Atto 488)
GRIN2B 适用: 大鼠 WB, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal S59 Atto 488

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (Atto 594)
GRIN2B 适用: 大鼠 WB, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal S59 Atto 594

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (Atto 390)
GRIN2B 适用: 大鼠 WB, IHC, IF, IP, ICC, AA 宿主: 小鼠 Monoclonal S59 Atto 390

应用备注

WB 1:300-5000
ELISA 1:500-1000

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
抗原

GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

别名

NMDAR2B

背景

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity).
Subcellular location: Cell membrane
Synonyms: MRD6, NR2B, hNR3, GluN2B, NMDAR2B, Glutamate receptor ionotropic, NMDA 2B, Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subunit 3, NR3, GRIN2B

基因ID

2904

UniProt

Q13224

途径

Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity