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PLCz1 抗体 (AA 351-450) (Cy5)

This Cy5-conjugated 兔 多克隆 anti-PLCz1 antibody specifically detects PLCz1 in IF (cc) 和 IF (p). The antibody is reactive with 大鼠 samples.
产品编号 ABIN801187
发货至: 中国
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Quick Overview for PLCz1 抗体 (AA 351-450) (Cy5) (ABIN801187)

抗原

See all PLCz1 抗体
PLCz1 (Phospholipase C zeta 1 (PLCz1))

适用

  • 21
  • 14
  • 4
大鼠

宿主

  • 35
  • 1

克隆类型

  • 35
  • 1
多克隆

标记

  • 13
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This PLCz1 antibody is conjugated to Cy5

应用范围

  • 12
  • 12
  • 12
  • 10
  • 7
  • 3
  • 3
  • 3
  • 2
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-450

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Cow,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human PLCZ1

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PLCz1 (Phospholipase C zeta 1 (PLCz1))

    别名

    PLCZ1

    背景

    Synonyms: PLCzeta, NYD-SP27, PLC-zeta-1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1, Phosphoinositide phospholipase C-zeta-1, Phospholipase C-zeta-1, Testis-development protein NYD-SP27, PLCZ1, PLCZ1_HUMAN

    Background: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.

    基因ID

    89869

    UniProt

    Q86YW0
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