GRIA2 抗体 (pSer880)
Quick Overview for GRIA2 抗体 (pSer880) (ABIN800898)
抗原
See all GRIA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer880
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预测反应
- Human,Mouse,Rat,Cow,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human Gria2 around the phosphorylation site of Ser880
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
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别名
- Gria2
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背景
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Synonyms: Glutamate receptor 2 PrecursorSer880, Gria2, Glur-2, GluR-B, Glur2, GluR-2, GluR-K2, Glutamate receptor 2, Glutamate receptor ionotropic, AMPA 2, glutamate receptor, ionotropic, N-methyl D-aspartate 1, NMDA receptor subunit , AMPA-selective glutamate receptor 2.
Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing(CAG->CGG, Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.
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基因ID
- 2891
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途径
- PI3K-Akt Signaling
抗原
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