CD163 抗体 (PE)
Quick Overview for CD163 抗体 (PE) (ABIN784617)
抗原
See all CD163 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Monoclonal antibody 5C6 FAT recognizes a membrane glycoprotein on human monocytes and macrophages which is expressed in intermediate and late inflammatory stages. The red R-Phycoerythrin label is particularly useful to avoid the greenish autofluorescence of some cells in their resting state.
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Affinity chromatography
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免疫原
- Human CD163
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- Phosphate buffered saline pH 7.2 (PBS), 0.09 % Sodium Azide, 10 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
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有效期
- 6 months
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- CD163
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别名
- CD163
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背景
- CD163 is a scavenger receptor for the haemoglobin-haptoglobin complex, and is upregulated by glucocorticoids and IL-10. The extracellular portion of the receptor is regularly shed and can be found in the circulation. An important function of CD163 seems to be in the adhesion of monocytes to activated endothelial cells. CD163-positive cells include skin histiocytes, Kupffer cells, spleen macrophages of the red pulp, and some thymus macrophages. The antigen is also found abundantly in human term placenta, and regularly in acute and chronic inflammatory lesions. The red R-Phycoerythrin label is particularly useful to avoid the greenish autofluorescence of some cells in their resting state.Synonyms: Hemoglobin scavenger receptor, M130, Macrophage marker, Scavenger receptor cysteine-rich type 1 protein M130
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基因ID
- 9332
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NCBI登录号
- NP_004235
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UniProt
- Q86VB7
抗原
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