GRM7 抗体 (pSer862)
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Quick Overview for GRM7 抗体 (pSer862) (ABIN784604)
抗原
See all GRM7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer862
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特异性
- Specific for the ~102k mGluR7 protein phosphorylated at Ser862. Immunolabeling is blocked by preadsorption of antibody with the phospho-peptide used as antigen but not by the corresponding dephosphopeptide.
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交叉反应 （详细）
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Species reactivity (expected):Bovine, Canine, Human, non-Human Primate and Zebrafish.
Species reactivity (tested):Mouse and Rat. -
纯化方法
- Affinity Chromatography.
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免疫原
- Phosphopeptide corresponding to amino acid residues surrounding phospho-Ser862 of Rat mGluR7.
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亚型
- IgG
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anti-Glutamate Receptor, Metabotropic 7 (GRM7) (AA 454-590) antibody
GRM7 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7G8D3 unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (AA 454-590) antibodyGRM7 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7G8A2 unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (C-Term) antibodyGRM7 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (N-Term) antibodyGRM7 适用: 人, 大鼠, 小鼠, 犬, Cow, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (N-Term) antibodyGRM7 适用: 人, 大鼠, 小鼠, 犬, 兔, Cow, 马, 猴, 小鸡 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (Extracellular Domain) antibodyGRM7 适用: 人, 大鼠, 小鼠, 犬, 兔, Cow, 马, 猴, Pig IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (AA 377-390), (Extracellular) antibodyGRM7 适用: 大鼠 WB, IHC, IF, FACS, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (C-Term) antibodyGRM7 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (N-Term) antibodyGRM7 适用: 人, Cow WB, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (C-Term) antibodyGRM7 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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注意事项
- Avoid repeated freezing and thawing.
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- GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
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别名
- mGluR7 / GRM7
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背景
- Metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. They are implicated in many forms of neural plasticity as well as learning and memory and drug abuse (Bhattacharya et al., 2004, Francesconi et al., 2004, Wilson and Nicoll, 2001). The mGluRs are divided into three groups based on sequence identity and pharmacological properties: group I (mGluR1 and mGluR5) are localized in the perisynaptic region of the postsynaptic membrane, whereas group II (mGlur2 and mGluR3) and group III (mGluR4,6,7 and 8) are localized predominantly at presynaptic terminals. PKC phosphorylation of serine 862 on mGluR7 has been shown to be critical for stabilizing receptor surface expression and promoting binding to the synaptic PDZ-domain-containing protein PICK1 (Suh et al., 2008).Synonyms: GPRC1G, MGLUR7, Metabotropic glutamate receptor 7
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基因ID
- 81672
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NCBI登录号
- NP_112302
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途径
- Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour
抗原
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