Histone H4 抗体 (acLys5)
Quick Overview for Histone H4 抗体 (acLys5) (ABIN784593)
抗原
See all Histone H4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- acLys5
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特异性
- This antibody detects endogenous levels of total Histone H4 protein only when acetylated at Lysine5.
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交叉反应 (详细)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Immunoaffinity Chromatography
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免疫原
- Synthetic peptide from Human Histone H4 around the acetylated site of Lys5.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS (without Mg2+, Ca2+), pH 7.4 containig 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- Histone H4
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背景
- Histone proteins H3, H4, H2A, and H2B function as building blocks to package eukaryotic DNA into repeating nucleosome units that are folded in higher order chromatin fibers. The nucleosome is composed of an octamer containing a H3/H4 tetramer and two H2A/H2B dimers, surrounded by approximately 146 base pairs of DNA. A diverse and elaborate array of post-translational modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation occurs on the N-terminal tail domains of histones.Synonyms: H4/A, H4FA, HIST1H4
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基因ID
- 121504
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NCBI登录号
- NP_001029249
抗原
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