Lactoferrin 抗体 (FITC)
Quick Overview for Lactoferrin 抗体 (FITC) (ABIN784364)
抗原
See all Lactoferrin (LTF) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- In immunoelectrophoresis against rhesus monkey milk a single precipitin line is obtained. The antiserum does not react with any other protein component of monkey serum or plasma. Cross-reactivity: The antiserum does not cross-react with any other monkey plasma proteins as tested in gel-diffusion techniques. Inter-species cross-reactivity is a normal feature of antibodies to plasma or milk proteins, since homologous proteins of different species frequently share antigenic determinants. Cross-reactivity of this antiserum has not been tested in detail, however a strong cross-reaction with lactoferrin in human milk has been observed.
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产品特性
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Absorption / Emission: 492nm/515nm
Molar Ratio: 1,6 -
纯化方法
- DEAE-column Chromatography
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免疫原
- Exocrine organs produce various secretions, each with its characteristic function. Proteins found in secretions may be divided into two groups: those specific for the particular secretion, and plasma proteins independent of the type of exocrine cells. Lactoferrin belongs to the first group. It is an iron containing protein with a molecular weight of 75,000 and it is antigenically different from transferrin. Lactoferrin has a slight antimicrobial action. Originally identified in milk, its presence has also been demonstrated in other secretions as saliva, semen and tears. The immunogen has been isolated from monkey milk. Freund’s complete adjuvant is used in the first step of the immunization procedure.
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亚型
- IgG
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anti-Lactotransferrin (LTF) antibody
LTF 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) (AA 25-352) antibodyLTF 适用: 山羊 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) antibodyLTF 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB22673 unconjugated
anti-Lactotransferrin (LTF) (AA 500-710) antibodyLTF 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) (AA 219-248) antibodyLTF 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB11921 unconjugated
anti-Lactotransferrin (LTF) (AA 63-193) antibodyLTF 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) (AA 28-351) antibodyLTF 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) antibodyLTF 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) (AA 25-352) antibodyLTF 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) (Internal Region) antibodyVerified LTF 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Restore with 1 mL sterile distilled water
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浓度
- 10 mg/mL
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缓冲液
- PBS, pH 7.2 No preservative added, as it may interfere with the antibody activity. No foreign proteins added.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Lactoferrin (LTF) (Lactotransferrin (LTF))
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别名
- Lactotransferrin
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背景
- Lactoferrin is an iron binding glycoprotein with an approximate molecular weight of 80 kDa. The protein has two iron binding domains each housing one Fe3+ and the synergistic CO32- ion. The crystal structure form of human lactoferrin at 2.2A resolution exhibits 5330 protein atoms, 2Fe2+, 2CO32- and 98 carbohydrate atoms. Lactoferrin is absorbed from intestine by apical side of the membrane and localized to the nuclei. Intravenous infusion of lactoferrin is protective against lethal doses of E coli and induce bacterimia by a mechanism that downregulates neutrophil TNF alfa secretion. Recombinant human lactoferrin (rhLF), expressed and extracted from rice seed, is being evaluated for use as a dietary supplement to treat iron deficiency and/or iron deficiency induced anemia. Lactoferrin has been shown to have a role in the immune system and in early development of the embryo. A specific receptor for lactoferrin binding has been implicated in the human fetal intestine. Early embryonic localisation of lactoferrin by IHC has suggested its presence in various tissues including intestinal epitheliuem, kiney, and various regions of the brain.Synonyms: EC=3.4.21, LF, LTF, Lactoferrin, Talalactoferrin
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基因ID
- 4057
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NCBI登录号
- NP_001186078
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途径
- Transition Metal Ion Homeostasis
抗原
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