USP6 抗体 (C-Term)
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Quick Overview for USP6 抗体 (C-Term) (ABIN784289)
抗原
See all USP6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- KISPLHHLQM ECSP
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特异性
- This antibody recognizes USP6/TRE2/TRE17
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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免疫原
- Peptide with sequence from the C Terminus of the protein sequence according to NP_004496.1. Genename: USP6
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anti-Ubiquitin Specific Peptidase 6 (USP6) (AA 1122-1359) antibody
USP6 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 6 (USP6) (AA 142-155) antibodyVerified USP6 适用: 人 ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 6 (USP6) (AA 2-89) antibodyUSP6 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1F5 unconjugated
anti-Ubiquitin Specific Peptidase 6 (USP6) antibodyUSP6 适用: 人, 大鼠, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 6 (USP6) (AA 1280-1310), (C-Term) antibodyUSP6 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB4277 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- USP6 (Ubiquitin Specific Peptidase 6 (USP6))
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别名
- USP6 / TRE2
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背景
- Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation. A chromosomal aberration involving USP6 is a common genetic feature of aneurysmal bone cyst, a benign osseous neoplasm. Translocation t(16,17)(q22,p13) with CDH11. The translocation generates a fusion gene in which the strong CDH11 promoter is fused to the entire USP6 coding sequence, resulting in USP6 transcriptional up-regulation.Synonyms: Deubiquitinating enzyme 6, HRP1, TRE-2, Ubiquitin carboxyl-terminal hydrolase 6, Ubiquitin thioesterase 6, Ubiquitin-specific-processing protease 6
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基因ID
- 9098
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NCBI登录号
- NP_004496
抗原
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