ENOS 抗体
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北京 101111
Quick Overview for ENOS 抗体 (ABIN784153)
抗原
See all ENOS (NOS3) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The antibody recognizes 140 kDa eNOS.
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交叉反应 (详细)
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Species reactivity (expected):Pig, Horse, Sheep, Cattle, Monkey.
Species reactivity (tested):Human, Mouse, and Rat. -
纯化方法
- Affinity Chromatography.
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免疫原
- Synthetic peptide surrounding amino acid 602 of Rat eNOS
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 30 % Glycerol, 0.5 % BSA, and 0.01 % Thimerosal.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody at -20 °C. For long term storage aliquot and freeze at -70 °C.
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- ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))
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别名
- NOS3
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背景
- ENOS (Endothelial nitric-oxide synthase) is an important enzyme in the cardiovascular system. eNOS is regulated by phosphorylation at multiple sites. The two most thoroughly studied sites are the activation site Ser1177 and the inhibitory site Thr495. Several protein kinases including Akt/PKB, PKA and AMPK activate eNOS by phosphorylating Ser1177 in response to various stimuli. In contrast, bradykinin and hydrogen peroxide activate eNOS activity by promoting Thr495 dephosphorylation.Synonyms: Constitutive NOS, EC-NOS, Endothelial NOS, NOS type III, Nitric oxide synthase, eNOS, endothelial
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基因ID
- 4846
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NCBI登录号
- NP_000594
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途径
- ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
抗原
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