ERP44 抗体 (Internal Region)
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- 抗原 See all ERP44 抗体
- ERP44 (Endoplasmic Reticulum Protein 44 (ERP44))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ERP44 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody reacts to the internal region of ERP44 / TXNDC4.
- 纯化方法
- Immunoaffinity chromatography
- 免疫原
- ERP44 antibody was raised against internal domain of human.
- Top Product
- Discover our top product ERP44 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- PBS containing 0.09 % sodium azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- ERP44 (Endoplasmic Reticulum Protein 44 (ERP44))
- 别名
- TXNDC4 / ERP44 (ERP44 产品)
- 别名
- PDIA10 antibody, TXNDC4 antibody, 1110001E24Rik antibody, AI849526 antibody, AL033348 antibody, Txndc4 antibody, BWK4 antibody, txndc4 antibody, zgc:77883 antibody, endoplasmic reticulum protein 44 antibody, ERP44 antibody, Erp44 antibody, erp44 antibody
- 背景
- TXNDC4/ERp44/KIAA0573 was identified via its interaction with Erol-Lalpha, which in turn has been shown to regulate oxidative protein folding by selectively oxidizing protein disulfide isomerase. TXNDC4 is induced during ER stress and forms mixed disulfides with both hEROs and cargo folding intermediates. Over expression has been shown to alter the equilibrium of the different Ero1-Lalpha redox isoforms suggesting that TXNDC4 may be involved in the control of oxidative protein folding. It has also been suggested that TXNDC4 senses the environment in the ER lumen because it modulates IP3R1 (1,4,5-triphosphate receptor type 1) activity thereby regulating cytosolic calcium concentrations and intraluminal conditions.Synonyms: Endoplasmic reticulum resident protein ERp44, KIAA0573, Thioredoxin domain-containing protein 4
- 基因ID
- 23071
- NCBI登录号
- NP_055866
- 途径
- Cell RedoxHomeostasis, SARS-CoV-2 Protein Interactome
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