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ERP44 抗体 (Internal Region)

This anti-ERP44 antibody is a 兔 多克隆 antibody detecting ERP44 in IHC (p). Suitable for 人.
产品编号 ABIN784030
发货至: 中国

Quick Overview for ERP44 抗体 (Internal Region) (ABIN784030)

抗原

See all ERP44 抗体
ERP44 (Endoplasmic Reticulum Protein 44 (ERP44))

适用

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宿主

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克隆类型

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多克隆

标记

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This ERP44 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    Internal Region

    特异性

    This antibody reacts to the internal region of ERP44 / TXNDC4.

    纯化方法

    Immunoaffinity chromatography

    免疫原

    ERP44 antibody was raised against internal domain of human.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    PBS containing 0.09 % sodium azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    ERP44 (Endoplasmic Reticulum Protein 44 (ERP44))

    别名

    TXNDC4 / ERP44

    背景

    TXNDC4/ERp44/KIAA0573 was identified via its interaction with Erol-Lalpha, which in turn has been shown to regulate oxidative protein folding by selectively oxidizing protein disulfide isomerase. TXNDC4 is induced during ER stress and forms mixed disulfides with both hEROs and cargo folding intermediates. Over expression has been shown to alter the equilibrium of the different Ero1-Lalpha redox isoforms suggesting that TXNDC4 may be involved in the control of oxidative protein folding. It has also been suggested that TXNDC4 senses the environment in the ER lumen because it modulates IP3R1 (1,4,5-triphosphate receptor type 1) activity thereby regulating cytosolic calcium concentrations and intraluminal conditions.Synonyms: Endoplasmic reticulum resident protein ERp44, KIAA0573, Thioredoxin domain-containing protein 4

    基因ID

    23071

    NCBI登录号

    NP_055866

    途径

    Cell RedoxHomeostasis, SARS-CoV-2 Protein Interactome
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