RGS4 抗体 (AA 1-188)
Our Local Distributor
北京 101111
Quick Overview for RGS4 抗体 (AA 1-188) (ABIN783994)
抗原
See all RGS4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-188
-
特异性
- Recognizes RGS4
-
交叉反应 (详细)
- Species reactivity (expected):Cow (97 %), Rat (97 %), Rabbit (96 %), Pig (96 %), Sheep (97 %)Species reactivity (tested):Human, Mouse.
-
纯化方法
- Antigen-Affinity Chromatography.
-
免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 188 of Human RGS4
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.43 mg/mL
-
缓冲液
- 0.1 M Tris, 0.1 M Glycine, 20 % Glycerol ( pH 7) containing 0.01 % Thimerosal as a preservative.
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- -20 °C
-
储存方法
- Store the antibody undiluted (in aliquots) at -20 °C.
-
-
- RGS4 (Regulator of G-Protein Signaling 4 (RGS4))
-
别名
- RGS4
-
背景
- Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37 % identical to RGS1 and 97 % identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]Synonyms: RGP4, Regulator of G-protein signaling 4
-
基因ID
- 5999
-
NCBI登录号
- NP_005604
-
途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
-