ITIH4 抗体 (C-Term)
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Quick Overview for ITIH4 抗体 (C-Term) (ABIN783974)
抗原
See all ITIH4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 890-903, C-Term
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序列
- C-SDDGRRTLRV QGND
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特异性
- This antibody is expected to recognize both reported isoforms (NP_002209.2, NP_001159921.1).
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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免疫原
- Peptide with sequence from the C Terminus of the protein sequence according to NP_002209.2 and NP_001159921.1. Genename: ITIH4
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ITIH4 (Inter alpha Globulin Inhibitor H4 (ITIH4))
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别名
- ITIH4
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背景
- The inter-a-trypsin inhibitor (ITI, IaI) family, a typical and classical example for protein-glycosaminoglycanprotein (PGP) complexes, occurs constitutively in plasma at relatively high concentrations and is a result of alternate combinations of three kinds of heavy chains with a common light chain, the bikunin proteoglycan. Bikunin has two proteinase inhibitor domains and belongs to the Kunitz-type protease inhibitor family, it displays an inhibitory activity against trypsin, leukocyte elastase and plasmin. The heavy chains do not have any protease inhibitory properties but have the capacity to interact in vitro and in vivo with hyaluronic acid and this binding promotes the stability of the extra-cellular matrix. The ITI protein family is suspected of playing a key role in the extra-cellular matrix biology.Synonyms: Gp120, IHRP, ITI heavy chain H4, ITI-HC4, ITIHL1, Inter-alpha-inhibitor heavy chain 4, Inter-alpha-trypsin inhibitor family heavy chain-related protein, Inter-alpha-trypsin inhibitor heavy chain H4, PK120, Plasma kallikrein sensitive glycoprotein 120
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基因ID
- 216
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NCBI登录号
- NP_002209
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途径
- Glycosaminoglycan Metabolic Process
抗原
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