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SMC2 抗体 (C-Term)

The 山羊 多克隆 anti-SMC2 antibody (ABIN783969) specifically detects SMC2 in WB 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN783969
发货至: 中国
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Quick Overview for SMC2 抗体 (C-Term) (ABIN783969)

抗原

See all SMC2 抗体
SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

适用

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宿主

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山羊

克隆类型

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多克隆

标记

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This SMC2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
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    C-Term

    序列

    C-SKAKPPKGAH VEV Remarks: Reported variants NP_006435.2, NP_001036015.1 and NP_001036016.1 represent identical protein

    特异性

    Recognizes SMC2/CAPE.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

    免疫原

    Peptide with sequence from the C Terminus of the protein sequence according to NP_006435.2. Genename: SMC2
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

    别名

    SMC2 / CAPE

    背景

    CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behaviour of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in human cells.Synonyms: CAP-E, Chromosome-associated protein E, SMC protein 2, SMC-2, SMC2L1, Structural maintenance of chromosomes protein 2, XCAP-E homolog

    基因ID

    216

    NCBI登录号

    NP_006435
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