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GFAP 抗体

This anti-GFAP antibody is a 兔 多克隆 antibody detecting GFAP in IHC (p). Suitable for 人, 大鼠, 小鼠, Cow, 小鸡, 豚鼠, 绵羊, 猴 和 Hamster.
产品编号 ABIN783875
发货至: 中国

Quick Overview for GFAP 抗体 (ABIN783875)

抗原

See all GFAP 抗体
GFAP (Glial Fibrillary Acidic Protein (GFAP))

适用

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人, 大鼠, 小鼠, Cow, 小鸡, 豚鼠, 绵羊, 猴, Hamster

宿主

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克隆类型

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多克隆

标记

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This GFAP antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody recognizes Glial Fibrillary Acidic Protein (GFAP). Cellular localization: Cytoplasmic.

    交叉反应 (详细)

    Species reactivity (expected):Human, Mouse, Rat, Sheep, Monkey, Hamster, Guinea pig and Chicken.
    Species reactivity (tested):Bovine.

    纯化方法

    Purified

    免疫原

    GFAP isolated from cow spinal cord. Genename: GFAP

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM PBS, pH 7.4, 0.09 % Sodium Azide, 0.2 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    GFAP (Glial Fibrillary Acidic Protein (GFAP))

    别名

    GFAP

    背景

    Glial fibrillary acidic protein (GFAP) is an intermediate-filament (IF) protein that is highly specific for cells of astroglial lineage, although its tissue-specific role is speculative. GFAP has been located in rat kidney glomeruli and peritubular fibroblasts, leydig cells of testis, skin keratinocytes, osteocytes of bones, chondrocytes of epiglottis, bronchus, and stellate-shaped cells of the pancreas and liver. Its expression is essential for normal white matter architecture and blood-brain barrier integrity, and its absence leads to late-onset CNS dysmyelination. GFAP has also been shown to play a role in mitosis by adjusting the filament network present in the cell. During mitosis, there is an increase in the amount of phosphorylated GFAP, and a movement of this modified protein to the cleavage furrow.Synonyms: Glial Fibrillary Acidic Protein

    基因ID

    2670

    NCBI登录号

    NP_001124491
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