PKDCC 抗体 (Center)
This anti-PKDCC antibody is a 兔 多克隆 antibody detecting PKDCC in WB 和 EIA. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 2+ publications.
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(2 references)Quick Overview for PKDCC 抗体 (Center) (ABIN783833)
抗原
See all PKDCC 抗体
PKDCC
(Protein Kinase Domain Containing, Cytoplasmic Homolog (Mouse) (PKDCC))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This PKDCC antibody is un-conjugated
应用范围
Western Blotting (WB), Enzyme Immunoassay (EIA)
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抗原表位
- Center
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纯化方法
- Affinity chromatography
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免疫原
- 15 amino acid peptide from near the center of human VLK.
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anti-Protein Kinase Domain Containing, Cytoplasmic Homolog (Mouse) (PKDCC) (AA 1-294) antibody
PKDCC 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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: "Vertebrate Lonesome Kinase Regulated Extracellular Matrix Protein Phosphorylation, Cell Shape, and Adhesion in Trabecular Meshwork Cells." in: Journal of cellular physiology, Vol. 232, Issue 9, pp. 2447-2460, (2017) (PubMed).
: "A secreted tyrosine kinase acts in the extracellular environment." in: Cell, Vol. 158, Issue 5, pp. 1033-44, (2014) (PubMed).
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: "Vertebrate Lonesome Kinase Regulated Extracellular Matrix Protein Phosphorylation, Cell Shape, and Adhesion in Trabecular Meshwork Cells." in: Journal of cellular physiology, Vol. 232, Issue 9, pp. 2447-2460, (2017) (PubMed).
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- PKDCC (Protein Kinase Domain Containing, Cytoplasmic Homolog (Mouse) (PKDCC))
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别名
- PKDCC
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背景
- VLK was identified as a novel protein kinase that was induced after the differentiation of cultured embryonic stem cells into mesendoderm. It has no homologs in invertebrates, but is highly conserved in vertebrate species although it does not belong to any known protein kinase groups. VLK is initially expressed in E-cadherin-positive anterior visceral endoderm and mesendoderm, but its expression is later confined to E-cadherin-negative mesenchyme. It is enriched in the Golgi apparatus and is thought to regulate the rate of protein export from the Golgi. Targeted disruption of VLK in mice leads to a defect in lung development and neonatal lethality. It has been suggested that mutations in VLK may be associated with the allergic condition atopy.Synonyms: LOC91461, Protein kinase domain-containing protein, Protein kinase-like protein SgK493, Sugen kinase 493, VLK, Vertebrate lonesome kinase
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基因ID
- 91461
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NCBI登录号
- NP_612379
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UniProt
- Q504Y2
抗原
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