Transmembrane Protein 18 (TMM18) (C-Term) 抗体
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Quick Overview for Transmembrane Protein 18 (TMM18) (C-Term) 抗体 (ABIN783829)
抗原
See all Transmembrane Protein 18 (TMM18) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to Transmembrane protein 18.
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纯化方法
- Affinity chromatography
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免疫原
- 15 amino acid peptide near the carboxy terminus of human TMEM18.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- Transmembrane Protein 18 (TMM18)
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别名
- TMEM18
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背景
- Recent studies have examined how overexpression of certain genes enhances the tropism of neural stem cells (NSCs) for gliomas. Overexpression of Transmembrane protein 18 (TMEM18) provides NSCs and neural precursors an increased migration capacity towards glioblastoma cells in vitro and in the rat brain, while functional inactivation of the gene resulted in an almost complete loss of migration activity, suggesting that TMEM18 could be a potential target in NSC-based glioma therapy. Other recent results suggest that among others, the TMEM18 loci is associated with higher than normal body mass index (BMI) and obesity, indicating there may be a CNS-related role in predisposition to obesity. Multiple isoforms of TMEM18 are known to exist.Synonyms: Transmembrane protein 18
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基因ID
- 129787
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NCBI登录号
- NP_690047
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UniProt
- Q96B42
抗原
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