ZBP1 抗体 (C-Term)
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Quick Overview for ZBP1 抗体 (C-Term) (ABIN783819)
抗原
See all ZBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to ZBP1.
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纯化方法
- Affinity chromatography
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免疫原
- 18 amino acid peptide from near the carboxy terminus of human ZBP1.
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anti-Z-DNA Binding Protein 1 (ZBP1) (AA 10-167) antibody
ZBP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Z-DNA Binding Protein 1 (ZBP1) (AA 2-100) antibodyZBP1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2C10 unconjugated
anti-Z-DNA Binding Protein 1 (ZBP1) (AA 1-411) antibodyZBP1 适用: 人, 小鼠 WB, IP, ICC 宿主: 小鼠 Monoclonal Zippy-1 unconjugated
anti-Z-DNA Binding Protein 1 (ZBP1) (AA 144-193) antibodyZBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- ZBP1 (Z-DNA Binding Protein 1 (ZBP1))
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别名
- ZBP1
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背景
- Z-DNA binding protein 1 (ZBP1) belongs to a family of proteins that contain the Za domain which binds specifically to left-handed Z-DNA and Z-RNA. ZBP1 was initially identified as a novel gene that was up-regulated in activated macrophages in mice bearing ascites tumors, suggesting that is may play a role in processes such as host response in neoplasia. More recent reports indicate that the cytosolic ZBP1 has can act like the toll-like receptor TLR9 by detecting cytosolic double-stranded (ds) DNA and trigger induction of type I interferon and other innate immune responses. It is thought that the binding of ZBP1 to dsDNA enhances its association with innate immune response proteins such as the IRF3 transcription factor and the serine/threonine kinase TBK1 (also known as NAK). Multiple isoforms of ZBP1 are known to exist.Synonyms: C20orf183, DLM1, Z-DNA-binding protein 1
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基因ID
- 81030
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NCBI登录号
- NP_001153889
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UniProt
- Q9H171
抗原
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